Sep 2023 – Present · 2 yrs 8 mos · San Francisco Bay Area · On-site

• Building exciting, high-impact products at stealth company

Jul 2022 – Oct 2023 · 1 yr 3 mos · San Francisco Bay Area

• Leading a team of three computational biologists and two experimentalists to develop precision medicines for autoimmune disease
• Own analysis of public data, internal data generation efforts, and target discovery
• Successfully enabled the creation of two pre-clinical assets, resulting in Series A fundraise

May 2021 – Jul 2022 · 1 yr 2 mos · San Francisco Bay Area

• Leading key components of Xenium, 10x Genomics' in situ platform for high-resolution spatial omics
• Provide fast-turnaround data analysis to enable assay development

Apr 2019 – May 2021 · 2 yrs 1 mo · San Francisco Bay Area

• Led a team of 6 computational biologists to build algorithms, software, and support assay-development efforts for CellPlex (10x Genomics multiplexing solution)
• Owned the customer experience (design/UX decisions) and achieved consensus by building wireframes and integrating feedback from internal stakeholders and customers
• Launched Cell Ranger 6.0 to enable customers to analyze CellPlex data
• Led custom analysis and designed nucleic acid assays to quantify biochemical processes involved in NGS assay development
• Developed detailed models and simulations to set product specifications
• 8 patents are under review and publicly available; multiple others in the pre-publication stage

May 2017 – Mar 2019 · 1 yr 10 mos · San Francisco Bay Area

• Computational biologist in a hybrid product-development and algorithm-development role.
• Key accomplishments include:
• Led the transition of the single-cell gene expression v3 product onto the NextGem microfluidic architecture, a key company priority
• Led the development of Feature Barcode Technology - enabled the direct quantification of cell-surface- protein or CRISPR sgRNA expression at single-cell resolution
• Developed algorithms and software for analyzing massively parallel CRISPR-based functional genomics screens

Jun 2016 – Jul 2016 · 1 mo · Woods Hole, MA

• Participant in the intense and immersive 7-week course on research in quantitative cell biology and biophysics.
• Led 3 independent research projects studying diverse organisms: the protist Stentor pyriformis, the nematode C. elegans, and the filamentous fungus Ashbya gossypii.
• Skills: Working with non-model organisms.

Aug 2015 – May 2017 · 1 yr 9 mos · San Francisco Bay Area

• Leading a collaboration to engineer transcriptional circuits for building synthetic patterns of gene expression in living fruit fly embryos.
• Developing novel technologies for simultaneous multiplexed live imaging of transcription.
• Genome editing using CRISPR/Cas9 for measuring the transcriptional dynamics of endogenous genes.
• Programming and maintaining automated scripts in Matlab for analyzing movies of transcription.
• Skills: Synthetic biology; Genetic engineering; CRISPR/Cas9 genome editing; Molecular biology; Molecular cloning; Fly genetics; Confocal microscopy; Mathematical modeling; Data analysis; Programming.

Jul 2011 – Jun 2013 · 1 yr 11 mos · Pasadena, CA

• Provided leadership, mental health support, conflict resolution, and academic counsel for 120 undergraduates living in a residential dormitory.
• Selected, trained, and managed a team of 10 upper-class counselors to function as peer mentors and sources of emotional support.

Jul 2009 – Jun 2015 · 5 yrs 11 mos · Pasadena, CA

• Led a multi-institutional collaboration for developing design principles, automated software for molecular design, and experimental techniques for engineering in vitro chemical networks.
• Developed Piperine, a Python-based software for automating the design of DNA molecules for building enzyme-free reaction networks. Used by research labs from 3 institutions.
• Using Piperine, demonstrated the first ever enzyme-free biochemical oscillator, resulting in a publication in Science
• Skills: DNA sequence design; Writing software for automating molecular design; DNA Nanotechnology; DNA biophysics; Spectrofluorimetry; DNA biochemistry; Mathematical modeling; Stochastic simulation

May 2008 – Jun 2009 · 1 yr 1 mo · Mumbai Area, India

• Developed quantitative models and Python-based software for automated prediction of portfolio performance and periodic re-balancing for global mutual/pension fund clients.
• Originated and maintained important components of Portfolio Web Bench, an analytics platform for facilitating equity trades by international clients.
• Skills: Portfolio construction and re-balancing; Python programming; Automating decision pipelines.