Maria Ksenia Witte

Founder

Berlin, Berlin, Germany7 yrs 1 mo experience

Key Highlights

  • Expert in deep tech venture building and funding.
  • Creator of the 4x4-TETRA Deep Tech Matrix.
  • Proven track record in science commercialization.
Stackforce AI infers this person is a Deep Tech and Innovation Management expert.

Contact

Skills

Core Skills

Innovation ManagementProject ManagementVenture BuildingFundraisingGuest LecturingBusiness ConsultingMentoringGrant WritingLife SciencesCustomer ServiceNanotechnologyGrants ManagementChemistry

Other Skills

Project ControllingEntrepreneurship DevelopmentAnalytical SkillsInnovation ConsultingStart-up ConsultingGxPEntrepreneurshipBusiness PlanningProposal WritingBusiness StrategyScientific CommunicationsEarly-Stage StartupsMaterials ScienceStrategic ThinkingStart-up Ventures

About

“Deep tech startups” don’t exist. That category was inherited from consumer software. Applying it to science commercialization has distorted how institutions evaluate progress, allocate resources, and define success. You cannot build technological sovereignty on a borrowed playbook. We keep asking why founders fail. The better question is: What are our institutions structurally optimized to produce? At Arise Innovations, I work with the stakeholder systems around science ventures: • public-private innovation programs, • venture studios, • investors, • corporate innovation units, and • policy-facing ecosystem actors. I assess how their internal short-term actions shape long-term outcomes across portfolios. This means analyzing how KPI systems, reporting cycles, budget sequencing, resource allocation, and governance logic interact over time, and what those interactions make more likely. Because strong programs and rational decisions do not automatically produce strong outcomes. When internal incentives compound in the wrong direction, even sensible systems can generate unintended portfolio effects. Based on 13+ years at the lab-to-market intersection, across 200+ deep tech ventures and 25+ international innovation initiatives, I built the 4x4 TETRA Deep Tech Matrix to model these structural interactions ex ante, before they surface as costly risk and change management issues. The model shows what an institution’s current architecture is statistically biased to produce over long deep tech horizons, and where targeted adjustments can improve defensibility, mandate renewal, and compounded outcomes without restructuring the system itself. This matters even more now because European innovation policy is moving away from activity and visibility metrics toward measurable market uptake, long-term impact, and explicit assessment of market access performance. Institutions increasingly need to show not just that programs are active, but that their frameworks are capable of producing durable outcomes under review. Learn how to work with us: https://arise-innovations.com/our-solution#work-with-us Institutions that do this early spend less, report more credibly, and defend mandate renewals more effectively. No reorganization. No new bureaucracy. No disruption. Just clarity on where the system works, where it does not, and where small changes have disproportionately significant effect.

Experience

Arise innovations

4 roles

Guest Lecturer

Apr 2025Present · 11 mos

  • Deliver lectures and workshops at universities and innovation academies such as TU Darmstadt x Wiesbaden Business School (HIGHEST Initiative).
  • Topics include capital architecture, strategic funding design, and the mindset shift required to make scientific ventures fundable and scalable.
Guest LecturingUniversity LecturingBusiness Consulting

Key Opinion Leader | Deep Tech Venture Building & Capital Systems

Promoted

Jun 2024Present · 1 yr 9 mos

  • Regularly invited to (closed-door) sessions, panels, and keynotes to challenge how deep tech is evaluated, funded, and accelerated across Europe.
  • Known for reframing venture building from a science-first, systems perspective and for questioning startup and VC logics that systematically fail scientific ventures. My work is used to align capital strategy, program design, and institutional decision-making with the physical and regulatory realities of deep tech.
  • Creator of the proprietary 4x4-TETRA Deep Tech Matrix™ framework, a science-first operating system for venture and capital sequencing in deep tech, developed through academic and applied research and now used by European innovation institutions, venture builders, and investment teams.
  • Contributions typically focus on:
  • why deep tech fails in patterns, not exceptions
  • how mis-sequenced capital and programs manufacture the Valley of Death
  • what institutions, investors, and accelerators must change to enable real translation from lab to market
  • Frequently invited where difficult conversations are required and surface-level answers no longer suffice.
Start-up Venturesventure buildingfundraisingCapital AcquisitionsVenture BuildingFundraising

Mentor & Advisor

Mar 2024Present · 2 yrs

  • Active mentor and advisor in leading programs including
  • ‣ MassChallenge,
  • ‣ EIT Health,
  • ‣ EIT Digital,
  • ‣ Life Science Factory,
  • ‣ INAM and
  • ‣ Startup Colors.
  • Guided dozens of deep tech ventures in securing multi-millions, structuring TRL-aligned capital stacks, and navigating market readiness.
MentoringBusiness CoachingBusiness ConsultingFundingBusiness Advisory Services

Founder & CEO | Deep Tech Systems Thinker | Making Science and Market Work Together

Oct 2017Present · 8 yrs 5 mos

  • Arise Innovations operates as a structural diagnostics and decision-governance layer for deep tech ventures support infrastructures and ecosystems.
  • Using my prioprietary system, I make visible where scientific ventures, portfolios, or programs are structurally mis-sequenced across evidence, industrialization, market formation, and capital. The work focuses on detecting irreversible risks early and governing decision order before capital, partnerships, or narratives harden in ways that increase collapse probability.
  • Rather than predicting outcomes or scoring teams, the system produces prescriptive diagnostics: what must be true before escalation is safe, where optionality is being destroyed, and which sequencing errors systematically drive deep tech failure between TRL 3–7.
  • In practice, this includes:
  • System-level diagnostics for ventures, portfolios, and programs to surface hidden constraints and dominant risk drivers
  • Explicit sequencing verdicts that govern when to proceed, pause, redesign, or stop
  • Evidence-anchored proof gates that define when equity, scale-up, or industrial commitments are structurally justified
  • Decision guardrails for stakeholders: policymakers, ICs, venture builders, and program leadership to prevent premature commitments
  • Licensing of the Operating System to accelerators, venture studios, investors, and institutions as shared decision infrastructure
  • The scientific foundation of 4x4-TETRA Deep Tech Matrix™ is mathematically grounded, non-AI-based, and has been independently certified as original R&D under OECD standards by the German Federal Ministry framework (BSFZ). It is published as the world’s first RD&I-certified operating system for evaluation, commercialization, and capital flow in science ventures.
  • Arise Innovations is not a consultancy.
  • It is an operating system for governing how deep tech is allowed to evolve.
Project ControllingGrant WritingInnovation ManagementNanotechnologyLife SciencesEntrepreneurship Development+16

Inam - innovation network for advanced materials

Technology Scouting | Grants Management | Strategy & Entrepreneurship Advisor for Deep Tech Startups

Jul 2024Present · 1 yr 8 mos · Berlin, Germany · Remote

  • INAM provides startups with innovative technologies in Advanced Materials and Deep Tech with curated support at each stage of their growth.
  • Technology Scouting for Circular Economy, Sustainability, Green Tech Solutions
  • Grants Management
  • Networking & Match Making
  • Mentoring science & tech startups in venture building.
  • Business Advisor in accelerator programs.
Innovation ManagementNanotechnologyLife SciencesAnalytical SkillsInnovation ConsultingStart-up Consulting+9

Audiocure pharma gmbh

In-House Consulting: Public Funding | R&D | QM | CMC Management | Strategy planning

Nov 2021Jul 2022 · 8 mos

  • Interdisciplinary leading of R&D projects (internal and external);
  • Management Consulting for Public Funding and Research Grants;
  • Research tax funding (DE: steuerliche Forschungszulage);
  • Project management: coordination of cooperation with external consultants and contractors.
Project ControllingGrant WritingLife SciencesEntrepreneurship DevelopmentStart-up ConsultingGxP+4

Berlin-chemie menarini

Project Manager Product Lifecycle Management

Jun 2021Oct 2021 · 4 mos · Berlin, Germany

  • Leadership of projects among R&D – Manufacturing – Product Registration,
  • Quality management and Regulatory Affairs,
  • Working in GxP environment, documentation, reporting,
  • Assistance in development and implementation of e-LIMS-system.
Life SciencesGxPProject ManagementChemistry

Nanopet pharma gmbh

Project Leader: Public Funding | R&D | Strategy planning

May 2019Apr 2021 · 1 yr 11 mos · Berlin, Berlin, Germany

  • Application for R&D public funding & research grants (Germany and Europe);
  • Administration of public funding: controlling & finance management;
  • Interdisciplinary leading of R&D projects;
  • Arrangement of project consortiums, partner acquisition;
  • Representing the company in networks, team lead.
Project ControllingGrant WritingInnovation ManagementNanotechnologyLife SciencesAnalytical Skills+10

Freie universität berlin

Project leadership R&D | Acquisition of public funding

Feb 2019Feb 2020 · 1 yr · Berlin Area, Germany

  • R&D Project leading, digital data management, finance management, research grant management;
  • Process development: upscale and downscale;
  • Team leadership, personnel training.
Project ControllingGrant WritingNanotechnologyProject ManagementProposal WritingScientific Communications+2

Ifp institut für produktqualität gmbh

Deputy Head Of Food Contact Materials

Oct 2017Sep 2018 · 11 mos · Berlin, Berlin, Germany

  • Service providing, team leadership, management of instruments
  • Method development, validation, writing of SOPs and working instructions, LIMS,
  • Data analysis and data management of over 600 assignments.
Project ControllingProposal WritingGrants ManagementProject ManagementGrant Writing

Technische universität berlin

Research Associate

Jan 2017Sep 2017 · 8 mos · Berlin, Berlin, Germany

  • R&D functional nanomaterials;
  • Project management;
  • Synthesis and Analysis.
Customer ServiceTeam LeadershipGxPProject ManagementChemistry

Humboldt-universität zu berlin

Student Assistant at School of Analytical Sciences Adlershof (SALSA)

Oct 2016Sep 2017 · 11 mos · Berlin, Berlin, Germany

  • Administrative activities on an international surface;
  • Responsible for administration of public funding;
  • Finances, controlling.
NanotechnologyProject ManagementScientific CommunicationsMaterials ScienceChemistry

Berlin-chemie ag

Student Assistant

Apr 2016Sep 2016 · 5 mos · Berlin, Berlin, Germany

  • Pharmacovigilance, quality assurance, GMP, Arzneimittelgesetz (AMG), audit, ISO, DIN
Project ControllingProposal WritingGrants ManagementProject Management

Freie universität berlin

Research Associate

Aug 2015Dec 2015 · 4 mos · Berlin, Berlin, Germany

  • Research activities and Bachelor thesis on topic "Silica nanoparticles with various porosity".
  • Nanomaterials, nanotechnology, electron microscopy (REM, SEM, STEM), IR-spectroscopy, UV-Vis-spectroscopy, Gas sorption (BET) surface area measurements
GxPChemistry

Sgs

Student Worker

Apr 2014Mar 2016 · 1 yr 11 mos · Berlin, Berlin, Germany

  • Environment Chemistry, Chemical Analysis, Lab Tech Activities, ISO, DIN, round robin test
Life SciencesGxP

Eurofins

Internship

Mar 2014Apr 2014 · 1 mo · Berlin, Berlin, Germany

NanotechnologyProject ManagementMaterials ScienceChemistry

Education

University of Potsdam

PhD — Advanced Functional Nanomaterials | Business Administration | Joint Program

May 2019Feb 2022

Technische Universität Berlin

Master of Science - MS — Chemistry

Jan 2015Jan 2017

Freie Universität Berlin

Bachelor of Science - BS — Chemistry

Jan 2012Jan 2015

Freie Universität Berlin

Law

Jan 2010Jan 2012

Berlin-Chemie Menarini AG

Quality Control & CMC

Jun 2021Aug 2021

FernUniversität in Hagen

Project Management

Oct 2018Feb 2019

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